Individualization of hypertension treatment: an expert review

Developing an Expert System for Diabetics Treatment Advices

Today, expert systems are widely applied in medicine for prognosis, diagnosis, checkup, and treatment of various kinds of diseases. A comprehensive system for the checkup and treatment of different types of diabetes is still lacking. This paper reports development of such a system, its validation, and its utility in facilitating medical decision-making and supporting self-care.

Individualization of Antihypertensive Drug Treatment

Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation. However, this approach was appropriate decades ago when several drugs had inconveniences that made their use in monotherapy inadvi...

Treatment of esophageal (noncardiac) chest pain: an expert review.

BACKGROUND & AIMS Chest pain is a common and frightening symptom. Once cardiac disease has been excluded, an esophageal source is most likely. Pathophysiologically, gastroesophageal reflux disease, esophageal dysmotility, esophageal hypersensitivity, and anxiety disorders have been implicated. However, treatment remains a challenge. Here we examined the efficacy and safety of various commonly u...

Treatment Individualization in Colorectal Cancer

Colorectal cancer has been characterized as a genetically heterogeneous disease, with a large diversity in molecular pathogenesis resulting in differential responses to therapy. However, the currently available validated biomarkers KRAS, BRAF, and microsatellite instability do not sufficiently cover this extensive heterogeneity and are therefore not suitable to successfully guide personalized t...

Review of the WHO expert committee report on arterial hypertension.